Type I IFN immunoprofiling in COVID-19 patients.
Identifieur interne : 000320 ( Main/Exploration ); précédent : 000319; suivant : 000321Type I IFN immunoprofiling in COVID-19 patients.
Auteurs : Sophie Trouillet-Assant [France] ; Sebastien Viel [France] ; Alexandre Gaymard [France] ; Sylvie Pons [France] ; Jean-Christophe Richard [France] ; Magali Perret [France] ; Marine Villard [France] ; Karen Brengel-Pesce [France] ; Bruno Lina [France] ; Mehdi Mezidi [France] ; Laurent Bitker [France] ; Alexandre Belot [France]Source :
- The Journal of allergy and clinical immunology [ 1097-6825 ] ; 2020.
Descripteurs français
- KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Betacoronavirus (MeSH), Femelle (MeSH), Humains (MeSH), Infections à coronavirus (immunologie), Infections à coronavirus (sang), Interféron de type I (immunologie), Interféron de type I (sang), Mâle (MeSH), Pandémies (MeSH), Pneumopathie virale (immunologie), Pneumopathie virale (sang), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH).
- MESH :
English descriptors
- KwdEn :
- Adult (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Betacoronavirus (MeSH), Coronavirus Infections (blood), Coronavirus Infections (immunology), Female (MeSH), Humans (MeSH), Interferon Type I (blood), Interferon Type I (immunology), Male (MeSH), Middle Aged (MeSH), Pandemics (MeSH), Pneumonia, Viral (blood), Pneumonia, Viral (immunology).
- MESH :
- chemical , blood : Interferon Type I.
- blood : Coronavirus Infections, Pneumonia, Viral.
- immunology : Coronavirus Infections, Interferon Type I, Pneumonia, Viral.
- Adult, Aged, Aged, 80 and over, Betacoronavirus, Female, Humans, Male, Middle Aged, Pandemics.
DOI: 10.1016/j.jaci.2020.04.029
PubMed: 32360285
PubMed Central: PMC7189845
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Electronic address: sophie.assant@chu-lyon.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Viel, Sebastien" sort="Viel, Sebastien" uniqKey="Viel S" first="Sebastien" last="Viel">Sebastien Viel</name><affiliation wicri:level="3"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Gaymard, Alexandre" sort="Gaymard, Alexandre" uniqKey="Gaymard A" first="Alexandre" last="Gaymard">Alexandre Gaymard</name><affiliation wicri:level="3"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon, France. Electronic address: alexandre.belot@chu-lyon.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Pons, Sylvie" sort="Pons, Sylvie" uniqKey="Pons S" first="Sylvie" last="Pons">Sylvie Pons</name><affiliation wicri:level="1"><nlm:affiliation>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite</wicri:regionArea><wicri:noRegion>Pierre-Bénite</wicri:noRegion><wicri:noRegion>Pierre-Bénite</wicri:noRegion></affiliation></author><author><name sortKey="Richard, Jean Christophe" sort="Richard, Jean Christophe" uniqKey="Richard J" first="Jean-Christophe" last="Richard">Jean-Christophe Richard</name><affiliation wicri:level="3"><nlm:affiliation>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Perret, Magali" sort="Perret, Magali" uniqKey="Perret M" first="Magali" last="Perret">Magali Perret</name><affiliation wicri:level="1"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite</wicri:regionArea><wicri:noRegion>Pierre-Bénite</wicri:noRegion><wicri:noRegion>Pierre-Bénite</wicri:noRegion></affiliation></author><author><name sortKey="Villard, Marine" sort="Villard, Marine" uniqKey="Villard M" first="Marine" last="Villard">Marine Villard</name><affiliation wicri:level="1"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite</wicri:regionArea><wicri:noRegion>Pierre-Bénite</wicri:noRegion><wicri:noRegion>Pierre-Bénite</wicri:noRegion></affiliation></author><author><name sortKey="Brengel Pesce, Karen" sort="Brengel Pesce, Karen" uniqKey="Brengel Pesce K" first="Karen" last="Brengel-Pesce">Karen Brengel-Pesce</name><affiliation wicri:level="1"><nlm:affiliation>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite</wicri:regionArea><wicri:noRegion>Pierre-Bénite</wicri:noRegion><wicri:noRegion>Pierre-Bénite</wicri:noRegion></affiliation></author><author><name sortKey="Lina, Bruno" sort="Lina, Bruno" uniqKey="Lina B" first="Bruno" last="Lina">Bruno Lina</name><affiliation wicri:level="3"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Mezidi, Mehdi" sort="Mezidi, Mehdi" uniqKey="Mezidi M" first="Mehdi" last="Mezidi">Mehdi Mezidi</name><affiliation wicri:level="3"><nlm:affiliation>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Bitker, Laurent" sort="Bitker, Laurent" uniqKey="Bitker L" first="Laurent" last="Bitker">Laurent Bitker</name><affiliation wicri:level="3"><nlm:affiliation>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Belot, Alexandre" sort="Belot, Alexandre" uniqKey="Belot A" first="Alexandre" last="Belot">Alexandre Belot</name><affiliation wicri:level="3"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon, France; Pediatric Nephrology, Rheumatology, Dermatology Unit, Hospices Civils de Lyon, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon, France; Pediatric Nephrology, Rheumatology, Dermatology Unit, Hospices Civils de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32360285</idno><idno type="pmid">32360285</idno><idno type="doi">10.1016/j.jaci.2020.04.029</idno><idno type="pmc">PMC7189845</idno><idno type="wicri:Area/Main/Corpus">001486</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001486</idno><idno type="wicri:Area/Main/Curation">001486</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001486</idno><idno type="wicri:Area/Main/Exploration">001486</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Type I IFN immunoprofiling in COVID-19 patients.</title><author><name sortKey="Trouillet Assant, Sophie" sort="Trouillet Assant, Sophie" uniqKey="Trouillet Assant S" first="Sophie" last="Trouillet-Assant">Sophie Trouillet-Assant</name><affiliation wicri:level="3"><nlm:affiliation>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France. Electronic address: sophie.assant@chu-lyon.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Viel, Sebastien" sort="Viel, Sebastien" uniqKey="Viel S" first="Sebastien" last="Viel">Sebastien Viel</name><affiliation wicri:level="3"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Gaymard, Alexandre" sort="Gaymard, Alexandre" uniqKey="Gaymard A" first="Alexandre" last="Gaymard">Alexandre Gaymard</name><affiliation wicri:level="3"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon, France. Electronic address: alexandre.belot@chu-lyon.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Pons, Sylvie" sort="Pons, Sylvie" uniqKey="Pons S" first="Sylvie" last="Pons">Sylvie Pons</name><affiliation wicri:level="1"><nlm:affiliation>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite</wicri:regionArea><wicri:noRegion>Pierre-Bénite</wicri:noRegion><wicri:noRegion>Pierre-Bénite</wicri:noRegion></affiliation></author><author><name sortKey="Richard, Jean Christophe" sort="Richard, Jean Christophe" uniqKey="Richard J" first="Jean-Christophe" last="Richard">Jean-Christophe Richard</name><affiliation wicri:level="3"><nlm:affiliation>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Perret, Magali" sort="Perret, Magali" uniqKey="Perret M" first="Magali" last="Perret">Magali Perret</name><affiliation wicri:level="1"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite</wicri:regionArea><wicri:noRegion>Pierre-Bénite</wicri:noRegion><wicri:noRegion>Pierre-Bénite</wicri:noRegion></affiliation></author><author><name sortKey="Villard, Marine" sort="Villard, Marine" uniqKey="Villard M" first="Marine" last="Villard">Marine Villard</name><affiliation wicri:level="1"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite</wicri:regionArea><wicri:noRegion>Pierre-Bénite</wicri:noRegion><wicri:noRegion>Pierre-Bénite</wicri:noRegion></affiliation></author><author><name sortKey="Brengel Pesce, Karen" sort="Brengel Pesce, Karen" uniqKey="Brengel Pesce K" first="Karen" last="Brengel-Pesce">Karen Brengel-Pesce</name><affiliation wicri:level="1"><nlm:affiliation>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite</wicri:regionArea><wicri:noRegion>Pierre-Bénite</wicri:noRegion><wicri:noRegion>Pierre-Bénite</wicri:noRegion></affiliation></author><author><name sortKey="Lina, Bruno" sort="Lina, Bruno" uniqKey="Lina B" first="Bruno" last="Lina">Bruno Lina</name><affiliation wicri:level="3"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Mezidi, Mehdi" sort="Mezidi, Mehdi" uniqKey="Mezidi M" first="Mehdi" last="Mezidi">Mehdi Mezidi</name><affiliation wicri:level="3"><nlm:affiliation>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Bitker, Laurent" sort="Bitker, Laurent" uniqKey="Bitker L" first="Laurent" last="Bitker">Laurent Bitker</name><affiliation wicri:level="3"><nlm:affiliation>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Belot, Alexandre" sort="Belot, Alexandre" uniqKey="Belot A" first="Alexandre" last="Belot">Alexandre Belot</name><affiliation wicri:level="3"><nlm:affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon, France; Pediatric Nephrology, Rheumatology, Dermatology Unit, Hospices Civils de Lyon, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon, France; Pediatric Nephrology, Rheumatology, Dermatology Unit, Hospices Civils de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author></analytic><series><title level="j">The Journal of allergy and clinical immunology</title><idno type="eISSN">1097-6825</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Betacoronavirus (MeSH)</term><term>Coronavirus Infections (blood)</term><term>Coronavirus Infections (immunology)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Interferon Type I (blood)</term><term>Interferon Type I (immunology)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (blood)</term><term>Pneumonia, Viral (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Betacoronavirus (MeSH)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Infections à coronavirus (immunologie)</term><term>Infections à coronavirus (sang)</term><term>Interféron de type I (immunologie)</term><term>Interféron de type I (sang)</term><term>Mâle (MeSH)</term><term>Pandémies (MeSH)</term><term>Pneumopathie virale (immunologie)</term><term>Pneumopathie virale (sang)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Interferon Type I</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Interféron de type I</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Coronavirus Infections</term><term>Interferon Type I</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Infections à coronavirus</term><term>Interféron de type I</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Betacoronavirus</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pandemics</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Betacoronavirus</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Pandémies</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term></keywords></textClass></profileDesc></teiHeader></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32360285</PMID><DateCompleted><Year>2020</Year><Month>07</Month><Day>16</Day></DateCompleted><DateRevised><Year>2020</Year><Month>09</Month><Day>22</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1097-6825</ISSN><JournalIssue CitedMedium="Internet"><Volume>146</Volume><Issue>1</Issue><PubDate><Year>2020</Year><Month>Jul</Month></PubDate></JournalIssue><Title>The Journal of allergy and clinical immunology</Title><ISOAbbreviation>J. Allergy Clin. Immunol.</ISOAbbreviation></Journal><ArticleTitle>Type I IFN immunoprofiling in COVID-19 patients.</ArticleTitle><Pagination><MedlinePgn>206-208.e2</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0091-6749(20)30578-9</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jaci.2020.04.029</ELocationID><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Trouillet-Assant</LastName><ForeName>Sophie</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France. Electronic address: sophie.assant@chu-lyon.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Viel</LastName><ForeName>Sebastien</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gaymard</LastName><ForeName>Alexandre</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon, France. Electronic address: alexandre.belot@chu-lyon.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pons</LastName><ForeName>Sylvie</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Richard</LastName><ForeName>Jean-Christophe</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Perret</LastName><ForeName>Magali</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Villard</LastName><ForeName>Marine</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brengel-Pesce</LastName><ForeName>Karen</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lina</LastName><ForeName>Bruno</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mezidi</LastName><ForeName>Mehdi</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bitker</LastName><ForeName>Laurent</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Belot</LastName><ForeName>Alexandre</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon, France; Pediatric Nephrology, Rheumatology, Dermatology Unit, Hospices Civils de Lyon, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>COVID HCL Study group</CollectiveName></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016422">Letter</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>04</Month><Day>29</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Allergy Clin Immunol</MedlineTA><NlmUniqueID>1275002</NlmUniqueID><ISSNLinking>0091-6749</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007370">Interferon Type 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